Investigating the Role of Extracellular Vesicles as Biomarkers in Prostate Cancer

Extracellular vesicles (EVs), including exosomes and microvesicles, are emerging as powerful tools for prostate cancer diagnosis, prognosis, and treatment monitoring. As carriers of molecular information from cancer cells, they serve as valuable liquid biopsy biomarkers for non-invasive cancer assessment

Dr. Diana Suhaiza Said, a medical doctor and PhD candidate at the Bioscience Institute, Universiti Putra Malaysia, is conducting research on protein biomarker discovery in prostate cancer using cell lines. With no universally established protocol for EV isolation, she has dedicated significant effort to optimize the process to ensure sample purity.

Characterizing EV markers is crucial for validating her findings, but traditional western blotting is both time-consuming and sample-intensive—posing a challenge given the limited availability of EV samples. The Jess automated western blot system, requiring only 3µL of sample, has transformed her workflow by maximizing sample utilization and accelerating turnaround time, enabling more efficient and reliable EV analysis while maintaining the integrity of her research

“Utilizing the Jess system not only significantly saves my time but also allows me to learn about this remarkable technology designed to aid a busy researcher like myself, ensuring optimal accuracy and results. The lab staff has been so dedicated in helping me out from scratch, collecting samples, giving details of the results and patiently entertain all I need for my thesis.”