JUN 8, 2025
Neuroprotective mechanism of flavonoid compound against MPTP-induced Parkinson's disease in mice model
By using the Jess automated Western blot system, we can simultaneously detect four key target proteins in each sample, significantly reducing the manual, labor-intensive workflow of traditional Western blotting. This efficiency not only saves time and sample volume but also enhances the reliability and reproducibility in our research
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons, leading to motor dysfunction and cognitive decline. While current treatments focus on symptom management, growing evidence suggests that flavonoids—a class of natural compounds with antioxidant and anti-inflammatory properties—may offer neuroprotective benefits and help slow disease progression.
Dr. Charles Gnanaraj, a scientist at the Faculty of Pharmacy & Health Sciences, Universiti Kuala Lumpur (UniKL), is investigating the neuroprotective properties of flavonoid compounds using an MPTP-induced Parkinson’s disease mouse model. To assess the effects of flavonoid treatment, he analyzes key molecular markers associated with neurodegeneration.
By using the Jess automated Western blot system, we can simultaneously detect four key target proteins in each sample, significantly reducing the manual, labor-intensive workflow of traditional Western blotting. This efficiency not only saves time and sample volume but also enhances the reliability and reproducibility of our research.